Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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1,726 – 1,740 of 4,235 results

1,726

Ambeed S 4 9HFluoren9yl methoxy c

(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid, 84793-07-7, 98%

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1,727

Ambeed R 4Benzyl2oxazolidinone

(R)-4-Benzyl-2-oxazolidinone, 102029-44-7, 98%

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1,728

Medchemexpress LLC Imiquimod (maleate) | 896106-16-4 | 99.9% | 500 MG

Imiquimod maleate (R 837 maleate) is an immune response modifier and a selective toll-like receptor 7 (TLR7) agonist. It demonstrates antiviral and antitumor effects in vivo. This product is an analytical standard intended for research and analytical applications, and can be used for research of external genital, perianal warts, cancer, and COVID-19, and to induce psoriasis models.

Selective toll-like receptor 7 (TLR7) agonist
Exhibits antiviral and antitumor effects in vivo
Suitable for research of external genital, perianal warts, cancer, and COVID-19
Can be used to induce psoriasis models
Targets TLR7 and HSV-1

Pricing & Availability

1,729

Medchemexpress LLC Dihydroergotamine mesylate | 6190-39-2 | 99.94% | 50 MG

Dihydroergotamine mesylate is a BBB-permeable ergot alkaloid for the research of migraines. It reduces cell survival in A549 and NCI-H226 cells and inhibits cell survival in Hep3B, PLC/PRF/5, Huh7, and HepG2 cells.

Reduces cell survival in A549 and NCI-H226 cells
Inhibits cell survival in Hep3B, PLC/PRF/5, Huh7, and HepG2 cells
Induces mitochondrial morphologic alterations and dysfunction
Increases ROS generation and induces apoptosis
Disturbs ATP production in A549 cells
Inhibits STAT3 activation and enhances protein stability of Mcl-1

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1,730

Medchemexpress LLC BSJ-03-204 (triTFA) | 99.9% | 1174.97 | 25 MG

BSJ-03-204 triTFA is a PROTAC connected by ligands for Cereblon and CDK. It is a potent and selective Palbociclib-based CDK4/6 dual degrader, with IC50s of 26.9 nM for CDK4/D1 and 10.4 nM for CDK6/D1. This compound does not induce IKZF1/3 degradation and demonstrates anti-cancer activity.

PROTAC connected by ligands for Cereblon and CDK.
Potent and selective Palbociclib-based CDK4/6 dual degrader.
Demonstrates potent anti-proliferative effects on MCL cell lines.
Induces a G1 arrest.
Selectively degrades CDK4/6 in WT cells without affecting IKZF1/3 degradation.
Exhibits anti-cancer activity.

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1,731

Medchemexpress LLC Quin-C7 | 871100-12-8 | MFCD34182190 | 99.8% | 431.48 g/mol | C25H25N3O4 | 100 MG

Quin-C7 is an orally active FPR2/ALX antagonist used in anti-inflammatory research, including dextran sulfate sodium (DSS)-induced colitis models. It is provided as a high-purity solid with characterized solubility and storage recommendations for both in vitro and in vivo studies.

Orally active FPR2/ALX antagonist for anti-inflammatory research.
Demonstrated efficacy in DSS-induced colitis models.
High purity (≈99.8%) for reliable experimental results.
White to off-white solid form, suitable for standard handling and storage.
Soluble in DMSO at high concentration and formulatable for in vivo dosing.

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1,732

Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | 98.36% | 5 G

Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. It is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine also acts as a K+ channel blocker with an IC50 of 19.9 μM, and it can induce apoptosis. It can be used for malaria research.

Antiarrhythmic agent: Helps in the treatment of irregular heartbeats.
Potent, orally active, selective cytochrome P450db inhibitor: Targets and inhibits specific cytochrome P450 enzymes.
K+ channel blocker: Blocks potassium channels with an IC50 of 19.9 μM.
Induces apoptosis: Capable of triggering programmed cell death.
Used for malaria research: Applicable in studies related to malaria.

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1,733

TARGETMOL CHEMICALS INC THONZONIUM BROMIDE 50MG

Also available in 5 mg 10 mg 25 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Thonzonium bromide is a mono-cationic surfactant that is structurally similar to Farnesol as an antimicrobial agent. It inhibits proton transport in a dose-dependent manner (EC50=69 uM). It inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo. purity: 99%

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1,734

Ambeed Benzofuran2 3H one

Benzofuran-2(3H)-one, 553-86-6, 98%

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1,735

Medchemexpress LLC Sulfo-SPP | 452072-27-4 | 97.1% | 420.48 g·mol⁻1 | C14H16N2O7S3 | 5 MG

Sulfo-SPP is a heterobifunctional, thiol-cleavable, membrane-impermeable crosslinker used as an ADC linker in bioconjugation research. It reacts selectively with primary amines and contains a cleavable disulfide linkage that enables release under reducing conditions. Supplied for research use only.

Heterobifunctional thiol-cleavable crosslinker.
Membrane impermeable sulfonate group improves aqueous solubility.
Cleavable disulfide linkage for controlled release under reducing conditions.
Suitable for antibody-drug conjugate and bioconjugation applications.
Available in small pack sizes for research use.

Pricing & Availability

1,736

Medchemexpress LLC Azido-PEG9-amine | 1207714-69-9 | MFCD30723241 | 98.5% | 482.57 g/mol | C20H42N4O9 | 100 MG

Azido-PEG9-amine is an azide-terminated nine-unit polyethylene glycol (PEG) linker with a terminal primary amine used for bioconjugation and linker design. It is suitable for click chemistry and linker-based constructs, providing hydrophilic spacing between functional groups.

Azide-terminated PEG linker compatible with CuAAC and SPAAC click reactions.
Contains a primary amine for orthogonal functionalization.
Nine ethylene glycol units provide hydrophilicity and spacing for conjugates.
Reported high purity supports conjugation and analytical workflows.
Available in small research-scale quantities for method development.

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1,737

Medchemexpress LLC Alimemazine hemitartrate | 4330-99-8 | 98.4% | 200 MG

Alimemazine hemitartrate is an antagonist of the histamine (HA) receptor that also acts as a partial agonist at other GPCR receptors. This compound exhibits anti-serotonin, antispasmodic, antihistamine, sedation, hypnotic, antiviral, and anti-nausea properties. It promotes pancreatic β-cell growth and improves diabetes in mice. This product is intended for research use only.

Acts as a histamine (HA) receptor antagonist
Functions as a partial agonist at GPCR receptors
Exhibits anti-serotonin, antispasmodic, and antihistamine properties
Offers sedative, hypnotic, antiviral, and anti-nausea effects
Promotes pancreatic β-cell growth
Improves diabetes in mouse models
Reduces SARS-CoV-2 induced syncytia formation
Inhibits SARS-CoV-2 in HEK293T/ACE2 and VeroE6/TMPRSS2 cells
For research use only

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1,738

Medchemexpress LLC Mal-amido-PEG9-acid | 2112731-43-6 | 99.5% | 250 MG

Mal-amido-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. These PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. This product is for research use only and has not been fully validated for medical applications.

PEG-based linker
Used in synthesis of PROTACs
Facilitates selective degradation of target proteins
Utilizes ubiquitin-proteasome system
Contains two ligands connected by a linker

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1,739

eMolecules 5470-96-2 | Ambeed | Quinoline-2-carboxaldehyde | 1g | 490500663 | A123039 | MFCD00075032 | 157.172 | C10H7NO

Ambeed | Quinoline-2-carboxaldehyde | 1g | 490500663 | A123039 | 5470-96-2 | MFCD00075032 | 157.172 | C10H7NO

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1,740

Medchemexpress LLC Propidium (iodide) | 25535-16-4 | 99.7% | 5 MG

Propidium Iodide (PI) is a nuclear staining agent that stains DNA. It is an analogue of ethidine bromide, emitting red fluorescence when embedded in double-stranded DNA. PI cannot pass through living cell membranes but can pass through damaged cell membranes to stain the nucleus. It is commonly used in detecting apoptosis or necrosis and in flow cytometry analysis.

Stains DNA
Emits red fluorescence when embedded in double-stranded DNA
Used in detection of apoptosis or necrosis
Commonly used in flow cytometry analysis

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Quinolines and derivatives

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Medchemexpress LLC Imiquimod (maleate) | 896106-16-4 | 99.9% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Dihydroergotamine mesylate | 6190-39-2 | 99.94% | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BSJ-03-204 (triTFA) | 99.9% | 1174.97 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Quin-C7 | 871100-12-8 | MFCD34182190 | 99.8% | 431.48 g/mol | C25H25N3O4 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | 98.36% | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC THONZONIUM BROMIDE 50MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Sulfo-SPP | 452072-27-4 | 97.1% | 420.48 g·mol⁻1 | C14H16N2O7S3 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Azido-PEG9-amine | 1207714-69-9 | MFCD30723241 | 98.5% | 482.57 g/mol | C20H42N4O9 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alimemazine hemitartrate | 4330-99-8 | 98.4% | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Mal-amido-PEG9-acid | 2112731-43-6 | 99.5% | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Propidium (iodide) | 25535-16-4 | 99.7% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More